The CA-125 blood test measures the level of Cancer Antigen 125 (CA-125) in your blood. CA-125 is a protein that may be elevated in ovarian cancer but can also be increased in a number of non-cancerous conditions. It is used to support the assessment of women with persistent symptoms that may be associated with ovarian cancer and to monitor women with an established diagnosis. CA-125 is not a screening or diagnostic test for ovarian cancer and should always be interpreted alongside your symptoms and, where appropriate, further investigations such as ultrasound.